With my E30/meth tune, which I regularly use as a DD, I can run consistent 12.2s, with a car seat in back and wheelspin off the line. I purposely leave the car seat in when I race, because it's fun to point it out at the track, a family sedan with a car seat running low 12's. I'm also using Firestone A/S tires (hey, I live in Minnesota).
I don't doubt that with better tires, low DA, good track prep and launch, I could break into the high 11's. I actually think I'm spraying too much meth right now, looking at my STFTs. I may dial it down a bit, see if that helps. I will be back at the track in October, so fingers crossed.
It would also help if my fat ass lost some weight, but that's more difficult than the other mods.