Lots of good info above, but, I'll defer to Livernois as i expect them to be the experts with their tune and recommendation. As evidenced by so many of you that are tuned with no issues, for years now, i pulled the trigger last fall.
3 bar, 4x, with stock thermostat here. I'm happy. In my opinion, the car should have been tuned this way from the factory. The engine response, shifting, etc. is much improved, very noticeable over stock.
I have noticed some odd moments with boost or shifting after a long time in DC traffic, which is a rarity for me (once since tuned).