The Intake Cleaner (IC) is used with the engine running, the Throttle Plate Cleaner (TPC) is used with the engine NOT running. So the IC actually makes it down the intake tract, while the TPC only attends to the throttle body itself.
Direct Quote from the Amazon product page:
EASY-TO-USE SOLUTION: 3 SIMPLE STEPS
Step 1 - 3M Intake System Cleaner: Follow the fresh intake hose to the outside of your engine's throttle body. Remove the hose boot clamp where it enters the throttle body with a screw driver to access the throttle plate. Insert the 3M Intake System Cleaner's attached hose past the throttle plate and slip the intake hose boot back on. With the help of an assistant, start the car engine while the work area is monitored. When the engine idle reaches 500-1,000 RPM, hold steady at this rate and spray the product's contents into the running engine. This process cleans intake manifolds, valves and combustion chambers. Use the entire can, which may take several minutes. Turn off the engine and remove the product hose.
Step 2 - 3M Throttle Plate and Carb Cleaner: Again, with the help of an assistant, place the vehicle ignition in the "Run" position, but with the engine NOT started, and depress the accelerator to expose both sides of the throttle plate. Spray both sides of the plate, as well as the throttle body with 3M Throttle Plate and Carb Cleaner. Wipe excessive cleaner away and/or let wet areas dry for a few minutes with the throttle plate open before you replace the fresh air hose boot, tighten it up. This process cleans your engine's throttle plate and lubricates key pivot areas.
Step 3 - 3M Complete Fuel System Cleaner: This last step continues the treatment of all critical fuel system components. Add 3M Complete Fuel System Cleaner to a full tank, at a recommended dilution ratio of one ounce of additive to each gallon of fuel. Start the engine, allowing it to idle for a few minutes before driving it for 10-15 minutes. 3M Complete Fuel System Cleaner cleans injectors, intake valves and an combustion chambers while your engine consumes this tank of gas.