I am not sure if anyone has tried this yet on their SHO. I used it for my Mustang a few years back with great results. I went from running 11.1-11.2 down to running 10.7- 10.8 consistently. Now I also had a dyno tune for it to take advantage of the higher octane. I used this for a year until I have a custom fuel cell made and installed in the trunk where I would run race gas at the track and 93 on the street. I tied the fuel line together and put a GT500 dual fuel pump in the fuel cell but I digress.
I think I will give this a try without a tune as these ECM's are much more adaptive than the 2005 Mustang was. You may hear that this will foul your plugs but I never saw any evidence of that. It is very easy to use at the track, I always waited until I was almost empty and then I would add this on the way to the track and then add the gas so it would mix real well before I got to the track.
Just another alternative if you do not want to run meth. I would love to get to Livernois and get a dyno tune for this to use exclusively at the track and may make that happen this year sometime.
Here is a link to the site and product.
http://torcoracefuel.net/pro-accelerator.html