Unfortunately or fortunately, I don't have issues with E-85 as I have yet to find any in Florida, at least locally.
When in Iowa, many stations have it, but it's SUMMER! I ran a mix (1/4 E-85-3/4 93 E-10) once at the strip this fall, but hard to tell it's effect as I had installed downpipes and Strip was only showing 1/8 mi info, even though it's a 1/4 mi strip. I saw a .1-.2 lowering of my times in 1/8 mi from Torrie's 93 basic canned tune, which in 1/4 several years ago, produced 13.5's. (2 bar sensor -NO spray) Also had some wheel hop on several runs using my 18"( Michelin Pilot Super Sports, which are quite worn, but the first time at strip with them - 70 deg temps. Hooked up best and best times were with T/C on... (this has happened before as T/C in Flex cannot be completely turned off.).