Our Bosch system components are e85 rated. In fact the twin force prototype ran on and was rated for e85.
Looking at our components vs bosch's flex fuel "system" the only difference seems to be ecm programming and a smaller fuel rail which I assume helps keep frp up.
The one part I've had a hard time referencing is the lpfp. I doubt they'd use the entire Bosch system minus the low pressure pump but then again, its Ford.
That being said, a top tier fuel should keep you in good shape. I've ran blends from 10 % to absurd and everything is good. No noise, no pump performance degradation, nothing. The 2013 saw over 25k of various e usage.
Now that I've said that my hpfp will probably explode and rip a hole in the space -time continuim....lol.
Next on my list of chemicals to play with is Archoil.....maybe a comparo with the MMO is in order, haven't used that stuff in a loooooong time.