2010 SHO Random Misfires (Different banks/cylinders)

[guitar333]

hi guys,

Saturday I had a misfire...pulled the codes and got:
Cylinder 2 misfire, P0087 (Fuel Rail/System pressure Too Low)  & P0130 (02 sensor circuit, bank 1)

Ran smooth and fine shortly after and then,

Monday I had a misfire:
Cylinder 4 misfire & P0150 (02 sensor circuit, bank 2)
Checked the codes again shortly after and also got a P0304 (C4 misfire) & P00C6 (fuel pressure too low cranking).
Also loaded OBDFusion and saw the Short Term Fuel Trims for bank 2 were about -29% during the misifre. B1 STFT was -12%~


It's running fine again now, but it's a matter of time before it happens again.
What would cause a random or intermittent misfire on different cylinders/banks?
I thought it was due to my leaky valve cover gaskets, but even after replacing the gaskets and plugs I still have an issue.

Thanks

[SHOdded]

Replace the Fuel Pump Control Module First.  I believe it is located under the rear seat.  There was a recall on FPCMs for certain years, but even if yours is not included, it is worth swapping out.  Usually you will see heat related failures on it.  The actual LPFP rarely fails.

After the swap, reset codes, and see what comes back.  Hopefully the injectors are fine.